Original Research ArticleInternational Journal of Basic & Clinical Pharmacology
Publication: Assessment of medication adherence and quality of life and their association with myocardial infarction during percutaneous coronary intervention
Int J Basic Clin Pharmacol. 2026;15(4):691-696.DOI10.18203/2319-2003.ijbcp20261956
Abstract
Background Myocardial infarction (MI) patients undergoing percutaneous coronary intervention (PCI) require careful management. Medication adherence and quality of life (QOL) are crucial for preventing future cardiovascular events. Optimizing these factors improves patient outcomes and long-term health.
Methods This prospective observational study was conducted over six months in omini hospital, Kurnool. A total of 70 hypertensive CKD patients were enrolled and divided into two groups: Group A received Cilnidipine 10 mg daily, and group B, received Telmisartan 40 mg daily. Patients were evaluated for changes in renal in systolic and diastolic blood pressure, renal function markers (serum creatinine, urea, uric acid, proteinuria), and incidence of adverse effects.
Results MI as a leading cause of death in India, predominantly affecting men aged 51-60 due to factors like changing lifestyles, dietary habits, family history, and social behaviors.
Conclusions MI has emerged as a major cause of mortality in India, particularly affecting men in the 51-60 age range due to shifting dietary patterns, sedentary lifestyles, genetic predispositions, and social habits. Patients treated with PTCA, in accordance with American Heart Association protocols, showed noticeable improvement in their QOL after a four-month follow-up, with male participants reporting more substantial progress compared to females. Medication adherence evolved positively especially among male patients in the target age group. This study emphasizes that stronger medication compliance plays a key role in enhancing post-treatment QOL.
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Affiliations
- St. Johns college of pharmaceutical sciences, Yemmiganur, Andhra Pradesh, India
- Department of Pharmacy Practice, St. Johns College of Pharmaceutical Sciences, Yemmiganur, Andhra Pradesh, India
- Department of Cardiology, Omni hospital, Kurnool, Andhra Pradesh, India
