Publication:

Evaluation of incorporation of bone allograft at the site of implantation in various clinical conditions along with its complications

Background Bone transplants have been used routinely in the present century for diverse purposes to unite fractures, fuse joints, and repair skeletal defects.

Methods Twelve patients with fracture, bone defect, deformity, difficulty in the fusion of bone, etc. were taken in the study for elective surgery with fresh frozen allograft in the orthopedics department with the incorporation of inclusion and exclusion criteria.

Results Out of 12 cases in this study, 7 cases were related to spinal fusion, 3 cases were of fractures with bone defects, 1 case of non-union neck femur fracture and 1 case was of revision hip arthroplasty with the acetabular bone defect. Seventy-five percent (9 patients) and 25% (3 patients) were graded fair and poor respectively in the preoperative phase. At 6 months, excellent results were obtained in 50% (6 patients), good in 25% (3 patients), fair in 25% (3 patients), while none were graded as poor in terms of clinical evaluation.

Conclusions Fresh frozen bone, a good source of abundant bone allograft, can be stored in -70° freezer for use in orthopedic surgery to fill any filling defect in the bone. Also, proper storage, better surgical technique, hospital infection control policy, antibiotic policy, preoperative use of antibiotics before surgery has a good clinical outcome.