Case ReportInternational Journal of Advances in Medicine

Publication:
A case report: Cleistanthus collinus (Oduvan) poisoning

Int J Adv Med. 2025;12(5):491-493.DOI10.18203/2349-3933.ijam20252535

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Abstract

Cleistanthus collinus-an extremely toxic plant has been reported to be used for deliberate self-harm in different parts of the country, notably South India. Toxins contained include Cleistanthin A and B arediphyllin derivatives and are known to cause neuromuscular blockade, type 2 respiratory failure, type 2 renal tubular acidosis, hypokalaemia, cardiac arrhythmias. We are presenting a case report where the poisoning was associated with type 2 respiratory failure, acute kidney injury, type 2 renal tubular acidosis, hypokalaemia, acute respiratory distress syndrome. The patient was managed with intravenous N-acetylcysteine, ventilatory support and multiple sessions of dialysis following which the patient after a prolonged stay of 29 days was discharged from the hospital.

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Affiliations

  1. Department of Internal Medicine, Aster DM Healthcare, Dubai, UAE
  2. Department of Internal Medicine, Amrita Institute of Medical Sciences, Kerala, India

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