Publication:

Correlation of prolactin and thyroid disorders in infertile women

Background The objective of the study was to review the impact of thyroid status on the fertility and to study the prevalence of hyperprolactinaemia in infertility.

Methods A total of 150 subjects were divided into 3 groups: 50 primary infertility, 50 secondary infertility and 50 controls. The incidence of hyperprolactinaemia and thyroid disorders was studied in all the three groups.

Results The incidence of hyperprolactinaemia was 41% in all infertile subjects (60% with primary and 22% in secondary infertility) and 6% in controls. The incidence of hypothyroidism was 17% in infertility (18% in primary and 16% in secondary infertility) and 8% in controls.

Conclusions In this study there is a positive correlation between increased prolactin levels and hypothyroidism and such patients’ exhibit ovulatory failure. All patients with infertility should undergo prolactin levels and thyroid profile.