Publication:

Impact of 90-day integrative therapy on ambulatory blood pressure parameters in patients with white coat effect: a preliminary retrospective observational study

Hypertension diagnosis based on clinic blood pressure measurements is often confounded by the white coat effect, leading to potential misclassification and overtreatment. Ambulatory blood pressure monitoring provides a more accurate assessment of true blood pressure patterns and therapeutic response. A retrospective, multicentric, observational study was conducted at Madhavbaug clinics across India from December 2022 to April 2025. Patients aged 18 years and above diagnosed with white coat effect on ambulatory blood pressure monitoring and participated in the Blood Pressure Management Program were studied. Data from day 1 was compared with data from day 90. A total of 12 patients were studied. Improvement in daytime ambulatory systolic blood pressure (day 1: 143.92±7.39 mmHg and day 90: 123.83±7.10 mmHg), nighttime ambulatory systolic blood pressure (day 1: 135.25±7.67 mmHg and day 90: 114.83±10.20 mmHg), daytime ambulatory diastolic blood pressure (94.42±5.87 mmHg and 79.83±6.91 mmHg), and nighttime ambulatory diastolic blood pressure (day 1: 86.50±8.07 mmHg and day 90: 72.00±10.53 mmHg) at 90 days were improved. Ayurveda and Panchakarma significantly decreased ambulatory blood pressure parameters and eliminated white coat effect in patients without adverse side effects. Controlled trials are needed to confirm the positive outcome of this promising alternative treatment for hypertension.