Original Research ArticleInternational Journal of Basic & Clinical Pharmacology
Publication: Exploring the efficacy of herbal toothpaste formulated with karanj, miswak and banana peel
Int J Basic Clin Pharmacol. 2026;15(1):92-98.DOI10.18203/2319-2003.ijbcp20254158
Abstract
Background Oral health is essential for maintaining overall well-being, as poor oral hygiene has been associated with various systemic diseases. Common issues such as halitosis, dental caries, and gum inflammation adversely affect quality of life. Conventional toothpastes often contain synthetic ingredients that may cause side effects, creating a growing need for natural alternatives. This study aimed to develop an herbal toothpaste using karanj (Millettia pinnata), miswak (Salvadora persica), and banana peel (Musa spp.), known for their antibacterial, anti-inflammatory, and antimicrobial properties.
Methods Active compounds were extracted from the botanicals using standard solvent extraction techniques. The extracts were characterized for their phytochemical constituents and incorporated into a toothpaste base optimized for pH, stability, texture, and consistency. The antimicrobial activity of the formulation was tested against common oral pathogens, Staphylococcus aureus and Escherichia coli. Additionally, a sensory evaluation was conducted to assess taste and foaming ability.
Results Phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, and phenolic compounds responsible for antimicrobial action. The herbal toothpaste exhibited significant antibacterial activity, showing inhibition zones comparable to some commercial formulations. Sensory evaluation results indicated favorable responses in terms of taste, texture, and overall satisfaction. The formulation remained stable in consistency and pH during the testing period.
Conclusions The herbal toothpaste formulated demonstrated strong antimicrobial efficacy. This study supports the potential of plant-based ingredients as safe, cost-effective, and eco-friendly alternatives to synthetic oral care products, promoting sustainable and holistic oral hygiene.
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Affiliations
- Department of General Medicine, AIIMS Raipur, Chhattisgarh, India
- Department of Biotechnology, Seth Phoolchand Agrwal Smriti Mahavidyalaya, Navapara, Rajim, Chhattisgarh, India
- Department of Biotechnology, Amity University, Raipur, Chhattisgarh, India
