Publication:

Evaluation of effective anti-tumarogenic dose of ethanolic leaves extract of Moringa oleifera Lam. in Ehrlich ascites carcinoma bearing mice

Background To evaluate the optimum protective and curative antitumarogenic dose of the ethanolic leaves extract of Moringa oleifera Lam (ELMO). variety against Ehrlich ascetic carcinoma (EAC) cells.

Methods The protective and curative antitumor activity of ELMO was evaluated against the EAC tumor model. The activity was assessed using survival time and increase in life span.

Results Oral administration of all the doses of treated ELMO shown significantly increased in mean survival time and percent of life span, in that 500 mg/kg body wt. shown highest significance.

Conclusions ELMO treated 500 mg/kg body wt. possesses showed antitumor activity.