Review ArticleInternational Journal of Basic & Clinical Pharmacology

Publication:
Animal models of anxiety: a review

Int J Basic Clin Pharmacol. 2023;12(1):134-141.DOI10.18203/2319-2003.ijbcp20223368

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Abstract

Anxiety is a disorder that affects the quality of life and also imposes a huge economic burden. Animal models of anxiety have widened our understanding of the pathophysiology behind anxiety and to identify newer pharmacological compounds. Every behavioral test has its own limitations, and there are ways to minimize these like environment and handling. This review lists various experimental models of anxiety based on unlearned ethological models, learned responses like the Vogel conflict test, and psychological and physical stress models.

Keywords

Affiliations

  1. Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

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