Original Research ArticleInternational Journal of Research in Medical Sciences

Publication:
Evaluation of the effects of Corchorus olitorius L. and Carapa procera in the treatment of obesity

Int J Res Med Sci. 2018;6(4):1078-1081.DOI10.18203/2320-6012.ijrms20181259

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Abstract

Background The obesity remains a pathology today which expands. It leads in its wake much pathology with very serious consequences. It is therefore necessary to take steps to curb this nutritional pathology. Thus, two plant species including Carapa procera and Corchorus olitorius have been tested to assess their effect on this pathology.

Methods Aqueous extracts of Carapa procera bark and Corchorus olitorius roots were tested on rats and biochemical parameters were evaluated. Besides, a chemical characterization was led.

Results These plant extracts contain bioactive molecules that have a regressive activity on the plasma levels of cholesterol, triglyceride and LDL-cholesterol. These bioactive molecules increase the level of HDL-cholesterol. These 2 species are non-toxic on renal, hepatic and pancreatic functions in view of the values of urea, creatinine and blood glucose.

Conclusions Of these 2 extracts, the aqueous extract of Corchorus olitorius is more active.

Keywords

Affiliations

  1. Laboratory of Cellular Biology, Pastor Institute, Abidjan, Côte d’Ivoire
  2. Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire
  3. Laboratory of Pharmacodynamics-Biochemical, UFR Biosciences, University Félix Houphouët-Boigny, Abidjan-Cocody, Côte d’Ivoire

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