Publication:

Medication-induced electrolyte imbalances: a call for increased awareness and vigilance

Electrolyte imbalances are a significant concern in clinical practice, often caused by medications such as diuretics, cardiovascular drugs, chemotherapy agents, and antibiotics. These imbalances can lead to serious complications, including cardiac arrhythmias and increased mortality. Key electrolytes like sodium, potassium, calcium, and magnesium play crucial roles in maintaining fluid balance, nerve function, and muscle contraction. Medications can disrupt electrolyte balance, causing hyponatremia, hyperkalemia, hypomagnesemia, and other imbalances. Risk factors include pre-existing kidney disease, heart failure, and concomitant use of multiple medications. Treatment involves discontinuing the causative medication, correcting electrolyte imbalances, and managing underlying conditions. This review analyzes drug induced electrolyte disorders, their consequences, and treatment options. Understanding the mechanisms of drug-induced electrolyte imbalances can help clinicians manage complex cases and provide effective care.