Publication:

Oxygen requirements in multisystem inflammatory syndrome in children admitted in tertiary care hospital of North India

Background Study was aimed to describe the oxygen requirements among children admitted as multisystem inflammatory syndrome in children (MIS-C) in Indira Gandhi Medical College, Shimla.

Methods We conducted a cross-sectional study, from January 2021 to July 2021, in the pediatric ward of Indira Gandhi Medical College (IGMC), Shimla. Children admitted with a diagnosis of MIS-C were included. Data regarding socio-demographic factors and oxygen requirements were extracted and analyzed using Epi Info V7 software.

Results A total 31 children diagnosed as MIS-C were included. Tachypnea was present in 18 (58.1%) respiratory distress in 15 (48.4%). Optimal oxygen saturation (SpO2) more than 94% in 9 (25.8%), 93-94% in 8 (25.8%), 91-92% in 5 (16.1%), 86-90% in 2 (6.5%), 81-85% in 4 (12.9%), 75-80% in 1 (3.2%), 71-75% in 1 (3.2%) and <60% in 1 (3.2%). Oxygen at the rate of 2 l/min in 1 (3.2%), 3 l/min in 2 (6.5%), 4 l/min in 1 (3.2%), 5 l/min in 5 (16.1%) and 10 l/min in 9 (29.0%), was given through nasal prong in 1 (3.2%), Venturi mask in 3 (9.7%), NRM in 7 (22.6%) and mechanical ventilation in 7 (22.6%). Duration was for 2 days in 4 (12.9%), for 3 days in 7 (22.6%), for 4 days in 3 (9.7%), for 7 days in 1 (3.2%), for 10 days in 1 (3.2%), for 11 days in 1 (3.2%) and for 13 days in 1 (3.2%). Ventilatory support was given to 7 (22.6%), for 4 days in 2 (6.5%), for 7 days in 2 (6.5%), for 10 days in 1 (3.2%), for 11 days in 1 (3.2%) and for 13 days in 1 (3.2%).

Conclusions Oxygen is a crucial component of MIS-C therapy, children, observing a dip in SpO2 level should immediately start oxygen therapy.