Publication:

Study of patients with diminished ovarian reserve and our approach to their treatment: retrospective analytic study

Background Diminished ovarian reserve (DOR) is a perplexing entity. For the physician, optimisation of all aspects of management is needed to fruitfully utilise the available pool of gametes and time.

Methods In this multicentric retrospective analytic study, we re-evaluated all cases of DOR. All aspects of management were critically assessed.

Results We saw that idiopathic DOR was the most common etiology. AMH titres are reflection of oocyte yield. Stop agonist-antagonist and micro dose flare gives a higher oocyte yield. More number of good quality blastocyst was available in antagonist cycles. Growth hormone as adjuvant is helpful in DOR cases.

Conclusions DOR needs special care and urgency in treatment. Appropriate selection of protocol and adjuvants to treatment gives adequate pregnancy rate.