Publication:

Titagen® for total wellness: results from a randomised, placebo controlled clinical study on adults for osteoarthritis, improvement in skin, nail and health

Background Fish collagen has been vital in functional food with natural bioactive compounds to offer potential therapeutic benefits. Titan biotech limited (TBL) has studied Titagen® as a nutraceutical to evaluate improvement in in adults looking to improve skin, hair, nail health and osteoarthritis.

Methods Two randomised, double blinded, placebo controlled clinical studies were conducted on Titagen® of  TBL. 48 adults were studied in each of the studies for a period of 90 days. Study 1 (SHN study) was conducted on adults looking to improve skin, hair and nail health with Titagen®  dose of 5g per day for 3 months-assessed, using assessments and questionnaire to evaluate skin improvement, hair growth and nail health. Study 2 (OA study) was conducted on adults with osteoarthritis with Titagen® dose of 10 g per day for 3 months-evaluated using assessments and questionnaires.

Results Results showed that Titagen® was better than placebo with statistically significant results in skin health (59.72% vs -51.39), 60 second hair comb test (27.15% vs 2.35%), hair health (18.06% vs -43.06%), nail health (62.50% vs -33.33%), Western Ontario and McMaster universities arthritis index (WOMAC) parameters (39.73% vs 1.72%), pain VAS (70.86% vs 4.21%), quality of life questionnaire (20.83 scores vs 7.31 scores), global impression of change scale results (2.75 vs 4.40). There were no adverse events related to Titagen® and is deemed safe for daily consumption.

Conclusions The clinical studies proved 5 g Titagen® for 90 days improved skin, hair and nail health, 10 g Titagen® for 90 days reduced pain, stiffness in joints and improved quality of life living with osteoarthritis.