Review ArticleInternational Journal of Research in Medical Sciences
Publication: Osmotic controlled drug delivery system (OSMO technology) and its impact on diabetes care
Int J Res Med Sci. 2021;9(1):303-309.DOI10.18203/2320-6012.ijrms20205861
Abstract
Recently, focus on the development of controlled release drug delivery system has increased, as existing drugs exhibit certain pharmacokinetic limitations. The major goal of designing sustained release formulations is to improve the drug performance by prolonged duration of drug action, decreased frequency of dosing and reduced side effects by using smallest quantity of drug administered by the most suitable route. Osmotic-controlled release oral delivery system (OSMO technology) is the most promising strategy based system for sustained delivery of drug. Drug can be delivered in a controlled manner over a long period of time by the process of osmosis. Osmotic drug delivery system appears to be a promising solution for the limitations of conventional extended release formulations by virtue of their distinguished technological features. The present review describes briefly about various controlled drug delivery systems with special focus on advantages of osmotic-controlled release oral delivery system related to diabetes therapy and improved compliance.
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Affiliations
- Department of Endocrinology, PGIMS Rohtak, Haryana, India
- Department of Endocrinology, Center for Diabetes and Endocrine Care, Bangalore Diabetes Hospital, Bangalore, Karnataka, India
- Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
- Department of Medicine and Endocrinology, Pondicherry Institute of Medical Sciences, Pondicherry, India
- Department of Endocrinology, Centre for Diabetes and Endocrine Care, National Highway Gulshan Nagar, Srinagar, Jammu and Kashmir, India
- Department of Medicine and Endocrinology, Shilpa Medical Research Centre, Dahisar East, Mumbai, Maharashtra, India
- Department of Pharmacology, Government Medical College, Nagpur, Maharashtra, India
- Department of Medical Affairs, Wockhardt Ltd, Mumbai, Maharashtra, India
