Publication:

Study of the association between co-morbidities with COVID-19 and resulting morbidity and mortality: a hospital-based study in Uttar Pradesh, India

Background The pandemicity caused by SARS-CoV-2 virus led to increased number of morbidity and mortality worldwide. The clinical conditions, and the population infected were varied. For a new disease like this, it is very important to collectively measure all the co-morbidities being faced by the patients so that clinical case in future can be improved. The objective of this present study was to conduct a retrospective analysis of the patients infected with COVID-19 and study their clinical conditions and consequences.

Methods The retrospective analysis of clinical conditions, comorbidities, complications etc. of COVID-19 infected patients (survived and not survived) was studied for the period 2020-2021.

Results Varied type of infections were observed, such as anaemia, systemic sepsis, lower respiratory tract infections (LRTI), hypertension (HTN), type 2 diabetes mellitus (T2DM), and type 1 respiratory failure (T1RF). Some of these comorbidities were interconnected and can be considered to be the cause of poor prognostic results and fast clinical deterioration. Cardiopulmonary arrest, cardiorespiratory failure, acute respiratory distress syndrome (ARDS), pneumonia and complications due to COVID-19 were the main reasons of death found in the cohort studied.

Conclusions The results highlight the significance of proactive management techniques for early identification of high-risk individuals, and integrated, multidisciplinary care approaches for patients with multiple morbidities.