Publication:

Influence of preconception paternal age on the spontaneous abortion: a retrospective study

Background Due to the frequency of chromosomal abnormalities in sperm with increasing male age, the effect of increasing father's age as a cause of miscarriage is plausible, but there are still not enough studies available. The purpose of this study is to evaluate the effect of paternal age on spontaneous abortion.

Method In a retrospective study conducted on the files in the archives of Shahid Sadoughi Hospital in Yazd from 2020 to 2021, we reviewed the cases of 824 nulliparous pregnant women without systemic diseases or any risk for abortion. All women were under 35 years old with singleton pregnancies and aborted their babies before 20 weeks. Information collected included paternal age and paternal BMI.

Results A total of 104 cases were included in this study. In 10 cases, paternal ages were 40 years. There was a significantly higher rate of abortion among paternal ages >40 years.

Conclusions Our study demonstrates that paternal age has an impact on abortion. The incidence of abortion increases among older fathers.