Publication:

Prevalence of type 2 diabetes association with rheumatoid arthritis among different obese and non-obese populations of Patna, India

Background Type 2 Diabetes mellitus (T2DM) is the most common non-communicable chronic diseases in developed and developing countries around the world. The study reported the prevalence of diabetes association with rheumatoid arthritis (RA) among different obese and non-obese populations of Patna, India.

Methods This clinic based descriptive study was conducted in Patna city from 1st August 2017 to 30th September 2018. A total 250 patients with diagnosed RA were enrolled. DM was defined according to the ADA recommendations as FBS ≥126mg/dl or oral glucose tolerance test OGTT2 ≥200mg/dl and HbA1c≥6.5. On the basis of the BMI calculated, patients were categorized either as obese or non-obese. Random diabetic detection was done to detect T2DM and followed by proper investigation at clinical laboratories. Patients also asked for hyperglycemic events during initial counselling.

Results Mean BMI in obese was found to be 29.22±3.22 and in non-obese it was 22.99±1.38 (p<0.001). Most of the patients had been type 2 diabetes for more than 5 years duration. In both genders, an increasing trend was observed in the prevalence of type 2 diabetes with increasing BMI. Among these, a total of 198 (79.2%) were found to have diabetes, 115 (58.08%) of these were obese and 83 (41.91%) non-obese (p=0.003).

Conclusions BMI is directly correlated to type 2 diabetes, as T2DM was significantly more common in obese patients with RA compared to non-obese patients with RA. Obese patients with RA had significantly more frequent diabetes.