Publication:

Adrenal gland metastasis - an unusual manifestation of cancer cervix

Cancer Cervix is the most common women related cancer in India. It mainly affects middle aged female of 40-55 years age group, largely attributed to HPV infection. Advances in radiation therapy, surgical techniques and chemotherapy, have resulted in improved survival rates. Still 20-30% patients with cancer cervix would develop recurrent or persistent disease. Although the typical manifestations of recurrent cervical carcinoma are pelvic masses and lymphadenopathy, less typical manifestations like solid organ metastases and peritoneal carcinomatosis also can occur. The increasing prevalence of these less typical manifestations is partially related to the use of intensive pelvic radiation therapy, resulting in a shift away from pelvic recurrence toward distant metastasis, as well as related to improvements in cross-sectional imaging techniques. This article describes a clinical case of a 40-year-old patient with cancer cervix, who achieved complete remission with concurrent chemo radiotherapy and 3 years later, she relapsed with adrenal metastasis.