Review ArticleInternational Journal of Clinical Trials

Publication:
The face of Sagliker’s syndrome in maxillofacial aspect: a brief review

Int J Clin Trials. 2025;12(2):176-180.DOI10.18203/2349-3259.ijct20251214

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Abstract

In the world of nephrology, Sagliker syndrome is a unique rarity whose mechanism of occurrence is still not known. A rare bone disease characterized by secondary hyperparathyroidism in patients with chronic renal failure, caused by improper treatment in the early stages of the disease with retention of phosphorus, vitamin D deficiency, and disturbed calcium-phosphorus metabolism, which result in increased parathyroid hormone levels. Patients present with short stature, severe changes of the skull and jaws as well as other skeletal deformities, dental anomalies, ''brown tumors'' in the mouth, hearing loss, and neuropsychiatric disorders. This review briefly covers the maxillofacial aspect and core of Sagliker’s syndrome.

Keywords

Affiliations

  1. Department of Oral Medicine & Radiology, SDKS Dental College & Hospital, Nagpur, Maharashtra, India
  2. Department of General Medicine, Indira Gandhi Government Medical College & Hospital, Nagpur, Maharashtra, India

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