Publication:

Association between before and during early pregnancy hypertension with the gestational diabetes mellitus prevalence: a prospective observational study

Background Type 2 diabetes mellitus and hypertension are both components of the metabolic syndrome and commonly occur together in individuals. It has been found that blood pressure (BP) predicted the development of incident type 2 diabetes independent of body mass index (BMI) and other known risk factors.

Methods All the women with preeclampsia from 30 weeks onwards were enrolled in the study. The umbilical artery (UA) systolic-diastolic (S/D) ratio >2 standard deviation (SD) or UA-pulsatility index (PI) and UA-resistive index (RI) >2SD were taken as abnormal. The middle cerebral artery (MCA) was visualised and cerebroumblical PI ratio calculated. MCA-RI 30 (years) and with history of hypertension and prehypertension should be strictly screened for GDM as GDM was found twice more common in pre-hypertensive and hypertensive group and GDM prevalence markedly increased as the age advanced.