Publication:

Outcome of induction of labour with dinoprostone at a teaching hospital in Nepal

Background Induction of labour has now become a common practice; this study was conducted to find the outcome of induction of labour in pregnant women in relation to: induction delivery interval, mode of delivery, maternal complications and fetal outcome.

Methods It was a hospital based prospective study conducted from April 2012 to March 2013. Singleton pregnancy of gestational age ≥37 weeks, with vertex presentation and Bishops Score <6 were the cases included for induction. Dinoprostone (0.5mg) intracervically was used for induction. The different outcome parameters were analyzed.

Results Of 100 cases enrolled, majority 93% were below 30 years, mean gestational age of induction was 40.7± 0.7weeks and 58% were primi gravida. Ante natal care visit of ≥3 was present only in 66%. At induction 55% had bishop score of (0-3) and rest had score of (4-5). Postdated pregnancy (67%) followed by hypertension (13%) were the two most common causes for induction. 58% required second dose of dinoprostone, and the induction delivery interval was 24.3±9.6 hrs. 63% of the induced labour progress for vaginal delivery. Fetal distress (56.4%) was the commonest indication for caesarean section (CS). 6% of the cases had postpartum hemorrhage. 13% of the delivered neonate required NICU care, of which 53.8% was moderately asphyxiated. There was no maternal or neonatal death.

Conclusions In pregnancy undergoing induction of labour, CS is not uncommon, and there are few chances of maternal and neonatal morbidities. Therefore, obstetrician should be vigilant to avoid any untoward events.