Publication:

Histopathological spectrum of sinonasal lesions

Background A variety of non- neoplastic and neoplastic conditions involve the nasal cavity and paranasal sinuses. Non-neoplastic conditions comprise bulk of these lesions and some of them clinically mimic neoplastic conditions. This study was conducted to analyse the histopathologic spectrum of sinonasal lesions.

Methods A total of 57 cases of sinonasal mass lesions received in department of pathology, world college of medical sciences and research hospital were evaluated. Patient details were obtained from histopathology forms and register. Histopathological examination was carried out according to standard protocol. Percentages and simple frequency tables were used for analysis.

Results Majority of the lesions were found in the nasal cavity (n=45) followed by paranasal sinus (n=12). Non-neoplastic (46 cases) lesions outnumbered neoplastic lesions (11 cases). Infective sinusitis (n=25) was the most common non-neoplastic lesion encountered. Among neoplastic, 6 lesions were benign and 5 were malignant.

Conclusions Nonneoplastic lesions are more common than neoplastic lesions. Clinical and radiological features may be overlapping, hence histopathological examination is essential for final diagnosis and further management.