Case ReportInternational Journal of Reproduction, Contraception, Obstetrics and Gynecology
Publication: Vulvar microinvasive squamous cell carcinoma arising in vulvar intraepithelial neoplasia 3 complicated by genital warts and systemic lupus erythematosus: a case report
Int J Reprod Contracept Obstet Gynecol. 2013;2(3):437-440.DOI10.5455/2320-1770.ijrcog20130938
Abstract
A patient suffering from long-term systemic lupus erythematosus attended with a complaint of recurrent genital warts. Perineal white-colored skin and a peri-anal papillary protrusion adjacent to the genital warts were biopsied and determined to be vulvar intraepithelial neoplasia (VIN) 3 and microinvasive squamous cell carcinoma (SCC), respectively. These lesions were locally excised. Human papillomavirus (HPV)-6 was detected in these lesions, including in the genital warts, while HPV-56 was detected only in the perineal VIN3 and peri-anal microinvasive SCC.
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Affiliations
- Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine. Department of Gynecology, Izumi Municipal Hospital, Osaka, Japan
- Department of Pathology, Izumi Municipal Hospital, Osaka, Japan
- Department of Urology, Izumi Municipal Hospital, Osaka, Japan