Publication:

Oligohydramnios sequence and a variant of Dandy-Walker syndrome

Dandy-Walker syndrome is frequently associated with disorders of other areas of the central nervous system, including absence of the area made up of nerve fibers connecting the two cerebral hemispheres (corpus callosum) and malformations of the heart, face, limbs, fingers and toes. In the diagnostic workup, ultrasound is reliable and accurate for making the diagnosis. For diagnostic purposes and confirmation of diagnosis, foetal MRI in utero also has been advocated. Further confirmation may be done with autopsy of neonate after birth. Most of the pregnancies are terminated after antenatal diagnosis on anomaly scan. However if born alive the survival depends on associated anomalies in other systems.