Publication:

Effect of omega-3 supplementation on serum lipids in patients on chronic hemodialysis

Background Considering the important of effects resulting from chronic hemodialysis in patients having renal insufficiency of which cardio-vascular effect is the most important, this study has been done to examine the complementary effects of omega lipid on lipid profile serum and systemic inflammation index in these patients.

Methods Patients in this study include two groups (intervention and control). They have been chosen from among the patient called on hemodialysis unit of Booali hospital. The interval group received one omega capsule daily and the control group received a placebo capsule one a day for three months. At the end, the results of lipid profile tests (including triglycerides (TG), low density lipoproteins (LDL) and high density lipoproteins (HDL)) and systemic inflammation index (C-reactive protein) compared before and after receiving the medicine.

Results In this study in interval group having omega3 despite decrease in TG and increase in HDL after three months there were no meaningful changes. In group receiving placebo only increase of HDL was meaningful and despite decrease in TG after receiving placebo these changes was meaningless.

Conclusions The results of this study showed that omega3 had no meaningful changes in lipidic profile of patients who were being hemodialysed.