Publication:

Calcific Inflammatory myofibroblastic tumour in the retroperitoneum of a child: a case report

Inflammatory Myofibroblastic Tumor (IMT) is a rare benign pseudosarcomatous lesion, characterized by inflammatory infiltrates admixed with myofibroblastic spindle cells. Initially only pulmonary locations were described, now extra-pulmonary sites are also well recognized. We present a case of a 3 year old female child who presented with history of flank pain, abdominal mass and intermittent fever of 1 year duration. Provisional diagnosis was neuroblastoma, but it turned out to be a retroperitoneal IMT with calcification. The patient was managed with surgical resection of the tumor and post-operative treatment with steroids as part of the tumour adherent to the inferior vena cava could not be resected. IMT is an uncommon neoplasm of uncertain biological potential. Both, retroperitoneal location and calcifications are rare presentations. Complete surgical resection remains the mainstay of treatment. Possible treatment of residual and recurrent tumours could be with steroids and anti-inflammatory drugs. Selected cases may need chemotherapy, the efficacy of which is not well documented. It has close resemblance to calcific fibrous pseudo-tumour and we have presented the differentiating features from review of literature.