Publication:

Fetal and maternal outcomes of gestational thrombocytopenia: an observational study

Background The most common cause of pregnancy-related thrombocytopenia is gestational thrombocytopenia. There is a paucity of studies showing the effect of GT in mothers and neonates in the Indian population. So the present study was done to find out maternal and fetal outcomes of gestational thrombocytopenia in a tertiary care centre.

Methods 92 pregnant women diagnosed with gestational thrombocytopenia with platelet count of less than 150000 were enrolled.  Women with hypertensive disorders, autoimmune diseases, acute and chronic kidney disease, infections like dengue fever were excluded. The participants were evaluated by taking detailed history, clinical examination and routine investigations like complete blood count. Demographic variables like age, parity and clinical details like when she was diagnosed with gestational thrombocytopenia and what was the platelet count were noted. Complete blood count-platelets were measured at the time of diagnosis. Patients were followed through the pregnancy   until delivery, various maternal factors were observed like oligohydramnios, IUGR, Antepartum hemorrhage, mode of delivery, post-delivery complications like PPH, incision site hematoma.  Neonatal outcomes studied were APGAR, birth weight, neonatal thrombocytopenia and NICU admission.

Results There was no positive correlation between mothers with gestational thrombocytopenia and adverse maternal, neonatal outcomes (age, liquor abnormalities, IUGR, mode of delivery, APH, PPH, incision hematoma, neonatal thrombocytopenia, APGAR, birth weight, NICU admissions).

Conclusions It’s concluded that women with gestational thrombocytopenia do not have any adverse antenatal, perinatal, intrapartum, postnatal and neonatal complications.