Original Research ArticleInternational Journal of Basic & Clinical Pharmacology
Publication: A study to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy
Int J Basic Clin Pharmacol. 2018;7(9):1803-1807.DOI10.18203/2319-2003.ijbcp20183493
Abstract
Background The aim of the present study was to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy.
Methods The total leucocyte count (TLC) and total platelet count (TPC) of thirty patients on chemotherapy were obtained before and after the administration of GM-CSF. The results were analysed retrospectively for the effect of GM-CSF on these parameters. Statistical analysis was done, and graphs were made by Libre office calc and Student’s T Test was used for comparison of data.
Results The study showed that EMGRAST-M had an impressive effect on both the platelet count and the leucocyte count.
Conclusions GM-CSF has a great therapeutic role in the enhancement of platelet count and leucocyte count in patients of cancer chemotherapy.
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Affiliations
- Department of Medical Oncology, Brahmanand Narayan Hrudyalay, Jamshedpur, Jharkhand Province, India
- Department of Pharmacology and Therapeutics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand Province, India
- Department of Surgery, Tinplate Hospital, Jamshedpur, Jharkhand, Province, India
