Publication:

Resolution of oxidative stress on dandruff scalps with Ayurvedic anti-dandruff regime: a clinical study

Background This study is aimed to evaluate the efficacy and safety of ayurvedic anti-dandruff regime (Indulekha - Svetakutaja oil and dandruff treatment shampoo) in the management of dandruff in healthy, Indian participants suffering from dandruff.

Methods A total of 53 subjects with clinically diagnosed moderate dandruff were selected based on inclusion and exclusion criteria. Study was conducted in 3 phases, wash-off phase for 2 weeks, treatment phase for 4 weeks, followed by a regression phase of 2 weeks (during which ayurvedic anti-dandruff regime was withdrawn). Participants applied anti-dandruff regime on their scalp as per the instructions provided.

Results After 4 weeks of treatment, ayurvedic anti-dandruff regime demonstrated a significant reduction in dandruff flakes in 100% of participants, resolution of scalp itch in 100% participants with reduced levels of histamines (by 30%) and oxidative stress marker on scalp as measured by 13-hydroxyoctadecadienoic acid (HODE) by 50%. There were no reported side effects like oiliness/redness/irritation, during treatment and regression phase.

Conclusions Ayurvedic anti-dandruff regime is a safe and highly effective solution designed to combat dandruff and oxidative stress on scalp, while simultaneously improved overall health of the scalp and hair.