Publication:

Evaluation of risk factors for lower extremity amputation in diabetic foot ulcer: a hospital based observational study in Northern India

Background The present prospective observational study was done to analyse the risk factors leading to minor or major lower extremity amputation (LEA) in diabetic patients.

Methods A 139 patients were divided into Group A (n=113) and Group B (n=26) who underwent minor and major LEA respectively.

Results Majority of the patients in group B were from rural and lower socioeconomic background.  Duration of diabetes (p=0.017) and  of DFU was significantly longer in group B (P <0.001) The pro-portion of patients with Wagner Grade 4 and 5  ulcer were significantly higher in group B than in group A (P <0.001) Wound infection and maggots were significantly higher in group B though polymicrobial infection was higher in group A. Biochemical investigations were abnormally altered but difference between two groups was not significant.

Conclusions Socioeconomic burden on the society due to LEA can be reduced by making diabetic patients aware of foot hygiene, regular medical check-up for control of diabetes and associated complications.