Publication:

Multifocal facial Rosai Dorfman disease with postsurgical recurrence

Rosai Dorfman disease (RDD) is a histiocytic proliferative disorder with massive painless lymphadenopathy that though is rare yet has been reported more than seldom. Our report aimed to emphasis on a case with multifocal facial involvement with postsurgical recurrence, which had not yet been reported and an approach to alleviate the patient’s symptoms and avert a fatal outcome. This study was a case report and literature review. A 19 year old female presented with swelling involving right sided cheek, periorbital region and bilateral nasal cavity with palatal perforation for last 6 months. She had a past history of debulking of orbital RDD. Contrast enhanced computed tomography revealed an extraconal mass of the right orbit and left nasal mass extending to the nasopharynx. Biopsy taken from the nasal masses showed RDD on histopathology and immunohistochemistry. Though the disease was self-resolving, this patient required radiotherapy as debulking was not sufficient for its multifocal presentation and was followed by palatal reconstruction.