Publication:

Dengue infection in pregnancy and outcome in a tertiary care centre

Background Dengue is a mosquito borne viral infection with significant disease burden across the country. With the recent resurgence of the disease, increasing number of people are affected including pregnant women. Risk of exposure is 1% in a given pregnancy in highly endemic areas. The objective is to study the morbidity and mortality profile of dengue in pregnancy on mother and neonate.

Methods It is a time bound retrospective study conducted on 25 pregnant women with positive dengue serology in Department of Obstetrics and Gynecology BMCRI Bangalore India between May to October 2016.

Results 25 seropositive dengue infected pregnant women were diagnosed in the period. Multiorgan failure leading to intrauterine fetal and maternal death occurred in one case of dengue shock syndrome at 28 weeks. Perinatal outcomes of the other cases were satisfactory. No cases of perinatal transmission to the neonate occurred.

Conclusions Pregnancies complicated by dengue infection needs close monitoring in a tertiary care for potential fetal and maternal complications. Early detection of the critical phase, with judicious fluid management can decrease the mortality and morbidity associated with dengue infection.