Review ArticleInternational Journal of Basic & Clinical Pharmacology

Publication:
Potential anticancer activity of some medicinal plants in vitro and in vivo study

Int J Basic Clin Pharmacol. 2022;11(6):680-691.DOI10.18203/2319-2003.ijbcp20222757

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Abstract

The public health burden caused by cancer is significant in both developing and developed nations. The ability of biological, chemical, or synthetic substances to prevent, inhibit, or stop the progression of carcinogenic is known as anticancer activity. To treat the condition, several synthetic drugs are utilized, however because of their toxicity, research is now being done to examine chemotherapeutic medicines produced from plants. A review of several in vivo and in vitro techniques for determining the anticancer activities of natural compounds from medicinal plants has thus been undertaken. In this study, 50 Indian anticancer medicinal plants from 35 families are presented, together with comprehensive data on the parts and extracts utilized, the model type employed, the cancer cell line types that were tested, etc. These plants are still utilized to treat numerous tumor forms, including lymphoma, sarcoma, leukemia, and carcinoma. All of plants are likely candidates for in vivo research since they have strong anticancer action in vitro.

Keywords

Affiliations

  1. Department of Internal Medicine, Kishanganj, Bihar, India
  2. Department of Pharmacology, M. G. M. Medical College, Kishanganj, Bihar, India
  3. Department of Biochemistry, Kishanganj, Bihar, India
  4. Global Health Care, Teghari, Kishanganj, Bihar, India

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