Publication:

Effect of carbetocin versus oxytocin in postpartum hemorrhage in vaginal delivery

Background Postpartum hemorrhage (PPH) is excessive bleeding after childbirth, defined as more than 500 ml after a vaginal birth. It can occur within 24 hours (primary PPH) or up to 12 weeks after delivery (secondary PPH). This study aims to observe the effect of carbetocin versus oxytocin in PPH in vaginal delivery.

Methods A prospective cohort study was conducted for a period of six months April 2024 to October 2024 for a study population postpartum hemorrhage in vaginal delivery.

Results A comparative analysis was conducted between the carbetocin and oxytocin groups in terms of age and body mass index (BMI). Both groups consisted of 50 participants each, representing 100% of their respective groups. When examining the history of chronic diseases, such as hypertension and diabetes, 20% of participants in the carbetocin group had a history of hypertension, compared to 16% in the oxytocin group. Similarly, 10% of participants in the carbetocin group had a history of diabetes, while 14% in the oxytocin group reported the same condition. Both comparisons showed no statistically significant differences, with p values of 0.524 and 0.631, respectively.

Conclusions This study found no statistically significant differences in maternal and obstetric characteristics, pregnancy complications, or labor and delivery outcomes between women treated with carbetocin and those treated with oxytocin.