Publication:

Erythema necroticans: a rare reaction pattern in leprosy

Leprosy reactions are rare expression of immunological perturbations that interrupt the usual chronic course and the clinical stability of patients with leprosy. They generally occur during anti-mycobacterial treatment and are characterized by the appearance of crops of brightly erythematous tender nodules or plaques. Erythema Necroticans (ENe) is an uncommon manifestation of Type 2 Erythema Nodosum Leprosum (ENL) reaction, encountered in lepromatous and borderline lepromatous cases of leprosy. Severe ENL can become vesicular or bullous and break-down and is termed Erythema Necroticans.