Publication:

Neurological manifestations of coronavirus disease: a literature review

In December 2019, coronavirus pandemic re-emerged. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been identified as the causation in series of acute pneumonia cases discovered in Wuhan in Hubei Province, China. This disease is officially named COVID-19 by WHO. Symptoms manifestation of COVID-19 range from fever, malaise, myalgia, headache, to respiratory system symptoms of cough, stuffy/runny nose, and difficulty breathing. In severe cases, it may result in ARDS. A case study has reported that COVID-19 may also have cardiovascular manifestation, i.e. life threatening arrhythmia. Although COVID-19 is a respiratory infection and cardiovascular event is the main cause of fatality, medical professionals must understand its neurological complications in order to reduce mortality rate in infected patients. Further researches on specific risk factors or determinant protective factors from the neurological symptoms are needed to reduce risk of complication in COVID-19 infection cases.