Case ReportInternational Journal of Basic & Clinical Pharmacology

Publication:
Self-medicated, satranidazole induced fixed drug eruption: a case report

Int J Basic Clin Pharmacol. 2020;9(12):1903-1905.DOI10.18203/2319-2003.ijbcp20205131

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Abstract

Fixed drug eruption (FDE) is described as the development of one or more annular or oval erythematous patches as a result of systemic exposure to a drug; these reactions normally resolve with hyperpigmentation and may recur at the same site with re-exposure to the drug. Repeated exposure to the offending drug may cause new lesions to develop in addition to lighting up the older hyperpigmented lesions. Here we present an interesting case of satranidazole induced FDE with a past history of FDE to the same drug 5 months back. Since the eruption occurred in the same site on re-exposure to the same drug, a diagnosis of FDE was made and causality assessment by Naranjo adverse drug reaction probability scale showed a certain relationship between the cutaneous adverse reaction and the offending drug

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Affiliations

  1. Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Karaikal, Puducherry, India

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