Original Research ArticleInternational Journal of Basic & Clinical Pharmacology

Publication:
Comparison of conjunctival autograft and amniotic membrane graft in reducing pterygium-induced corneal astigmatism

Int J Basic Clin Pharmacol. 2025;14(6):945-951.DOI10.18203/2319-2003.ijbcp20253367

Thumbnail Image
View on the journal's website(opens in a new tab)

Abstract

Background Pterygium is a common ocular surface disorder that not only affects cosmesis but also induces corneal astigmatism, leading to visual impairment. This study aimed to compare the effectiveness of CAG and AMG in reducing pterygium-induced corneal astigmatism and to evaluate postoperative complications associated with each technique.

Methods A prospective, comparative study was conducted on 60 patients with primary pterygium at the Upgraded Department of Ophthalmology, GMC, Jammu, from Oct.2016 to April 2017. Patients were randomly assigned to undergo pterygium excision followed by either CAG/AMG. Preoperative and postoperative assessments were conducted at multiple intervals up to six months.

Results Preoperatively, the mean pterygium size was similar in both groups. Postoperatively, corneal astigmatism showed a progressive decline in both groups. By the first postoperative day, astigmatism significantly decreased (p 0.05), indicating comparable efficacy in postoperative corneal curvature improvement. Postoperative complications were more frequent in the conjunctival autograft group, with significantly higher conjunctival hyperemia (63% vs. 26%, p=0.003), while other complications were comparable between groups.

Conclusions Both conjunctival autograft and amniotic membrane graft effectively reduced corneal astigmatism following pterygium excision.

Keywords

Affiliations

  1. Department of Ophthalmology, GMC, Udhampur, Jammu and Kashmir, India
  2. Department of Pharmacology, GMC, Udhampur, Jammu and Kashmir, India

Full item record