Review ArticleInternational Journal of Research in Dermatology

Publication:
Mindfulness and the Mediterranean diet as alternative therapies in ambulatory care of psoriasis

Int J Res Dermatol. 2025;11(6):560-570.DOI10.18203/issn.2455-4529.IntJResDermatol20253404

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Abstract

Psoriasis is a chronic disease marked by intense inflammatory processes and a significant emotional effect. The progression of long-term emotional stress and poor dietary intake is a crucial factor; therefore, it's vital to have whole-person care. In this context, mindfulness appears to be rising as a viable cooperative strategy with the potential to promote emotional stability and enhance patients' wellness. This study aimed to evaluate the outcomes of holistic therapy supported by the mediterranean diet and mindfulness (MBI) through a review of up-to-date scientific research. A methodical research was conducted in the PubMed database using the keywords: “psoriasis,” “types of psoriasis,” “factors and psoriasis,” “pathophysiology and psoriasis or inflammation,” “mindfulness and psoriasis,” “meditation and psoriasis,” “cytokines and psoriasis,” and “psoriasis diagnosis.” Articles published between 2020 and 2025, in English or Spanish, with full-text access and peer review, were included. A total of 57 articles were considered. Evidence compiled over the most recent 5 years supports that mindfulness and the Mediterranean diet are successful therapies in psoriasis disease and, together, can improve outpatient healing and time to treatment, particularly by modulating the expression and activity of cytokines, such as TNF-α, interleukins (IL-1β, IL -6, IL-8, IL-10, IL-17, IL-23), IFN-γ, and cortisol levels. The implementation of the Mediterranean diet and mindfulness represents an effective and viable alternative in the outpatient treatment of psoriasis, with a positive impact on physical and emotional health.

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Affiliations

  1. Department of Nursing, Sciences in Health Institute, Universidad Autónoma del Estado de Hidalgo, Pachuca Hidalgo, México
  2. Departament of Molecular Biology, Instituto Nacional de Cardiología “Ignacio Chávez”, Tlalpan, Mexico City, Mexico

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