Publication:

Histopathological pattern of endometrial biopsy in abnormal uterine bleeding

Background Abnormal uterine bleeding is a common complaint in most women of different ages that prompts seeking gynaecologic care. This study aimed to determine the type of endometrial patterns of the different age categories of women who presented as a case of abnormal uterine bleeding.

Methods This was a retrospective study conducted on 72 patients who were presented with abnormal uterine bleeding and had endometrial biopsy done in our hospital. The data on their age, presenting complaints, and comorbidities of all the women were collected. The patterns of endometrial changes were studied and classified in accordance to the FIGO classification.

Results Seventy-two women with abnormal uterine bleeding demonstrated a fluctuating pattern of ten endometrial pathologies distributed among five age groups in the range of 31 to 65 years. Maximum number of cases of AUB were noted in the age group of (36-50) years (56 cases, 77.7%). Most common observed histopathological pattern in this study was normal cyclical patterns including proliferative endometrium (29.16%) and secretory endometrium (22.22%).

Conclusions Histopathological examination of the endometrium shows a clear-cut differentiation between physiological and malignancy changes in the endometrium. Hence, endometrial sampling is considered the golden tool for accurate analysis of the endometrium.