Publication:

A cross sectional study of knowledge, practice and attitude of medical professionals regarding pharmacovigilance function

Background Pharmacovigilance is of core importance for the prevention of adverse effect by signal generation. It developed as a science and Practice. Central database collecting international reports helpful in generating signals, improving safety profile, prevention of future adverse effects, thus provide a key data to national drug regulatory to make regulation. It is not only a science but act as a law and regulation. Underreporting of ADRs by healthcare professionals remains a major problem. Clinician’s collaboration is needed to come up with the challenges of underreporting. Spontaneous reporting plays a cardinal role in Pharmacovigilance practice.

Methods Cross Sectional, questioner-based study, 56- postgraduates, 42- first year,60- Second year, 35- Third year students of Institute of Medical Sciences were included with prior consent and Ethical committee permission. Structured pre-test questioner on, Knowledge-10, Attitude-02, Practice-06 were asked. Seminar was conducted on the ‘Pharmacovigilance in India: current Scenario, Study material were distributed to students. Prior to seminar and one week after conduction of seminar again the questioner was distributed again, and the same study was conducted, the difference in the response and attitude after transformation of knowledge were recorded.

Results After transformation of knowledge 77% JR responded that ADR and medication both should be reported which was earlier only 31%. 80% JR replied that ADR should be reported as early as possible which was earlier 38%. It indicates that transformation of knowledge is a pillar to bring the change in practise. 100% second year students responded that they have seen ADR reporting form which was only 30% before seminar.

Conclusions Up gradation of Knowledge by seminar, research papers, awareness pamphlets, Apps will promote the reporting and will strengthen the signal generation systems.