Publication:

Risk factors of acute heart failure after the first episode of acute coronary syndrome

Background Factors that speed up the development of acute heart failure (AHF) after acute coronary syndrome (ACS), are understudied in developing country like India. Therefore, this study was aimed to determine the risk factor of heart failure (HF) among the post-ACS patients.

Methods This descriptive cross-sectional study was performed at Government General Hospital (GGH) Srikakulam, Andhra Pradesh, India. 108 patients who were admitted with HF cardiology unit of GGH after ACS from September 2023 to November 2024 were enrolled in the study. An established inclusion and exclusion criteria along with consecutive sampling technique were used for patients’ recruitment. A self-structured proforma was applied to gather data. Data analysis was done in the statistical package for the social sciences (SPSS) version 25.0.

Results HF was more prevalent among those post-acute coronary syndrome patients who had an age group with 40 years or above (69.23%), male gender (62.82%), anterior wall myocardial infarction (38.46%), reduced ejection fraction (67.90%), left anterior descending artery pathology (17.95%), absence of myocardial revascularization procedure (46.15%), diabetes mellitus (52.56%), hypertension (78.20%), anemia (53.85%), hyperlipidaemia (75.64%), and who had history of smoking (51.28%). A significant number of patients also had chronic kidney disease (23.10%).

Conclusions Factors such as an age group with 40 years or above, male gender, anterior wall myocardial infarction, reduced ejection fraction, left anterior descending artery pathology, absence of myocardial revascularization procedure, diabetes mellitus, hypertension, anemia, hyperlipidemia and history of smoking, all accelerate the development of HF among post-ACS patients.