Publication:

Rare neurological manifestation following hepatitis A infection: a report of 2 cases

Hepatitis A is the leading cause of acute viral hepatitis in developing countries. Extra-hepatic manifestation is very rare occurrence in Hepatitis A. We report 2 cases, one developing Acute Cerebellar Ataxia and another Opsoclonus Myoclonus Ataxia syndrome (OMAS). The former presented with Ataxia of acute onset one week after Hepatitis A infection. The patient did not have any neurological complication and responded to conservative management. The second patient was a 7-year-old girl presented with behavioral abnormality, jerky eye movements and ataxia with myoclonus following a Hepatitis A infection one week ago. Patient was treated with pulse dose methyl prednisolone followed by oral prednisolone and showed a prompt response. Neurological manifestation following Hepatitis A is a rare phenomenon.