Publication:

A comparison of buccal versus vaginal misoprostol administration for induction of first and second trimester abortion

Background Aim of study was to compare effectiveness, adverse effects and patient’s acceptability of buccal and vaginal routes of administration of misoprostol in 1st and 2nd trimester abortion, type of study-randomized control trial

Methods A total of 200 women with indications for abortion up to 20 weeks of pregnancy were enrolled over a period of 1 year and received misoprostol either through buccal (Group A) or vaginal (Group B) route. Each group containing 50 patients of first trimester and second trimester.

Results Incomplete abortion rate (25%) was significantly higher in vaginal group while drug related side-effects (47%), patients’ satisfaction and acceptability (82%) was higher in buccal group respectively.

Conclusions Buccal route may be preferred owing to a better complete abortion rate, better patient satisfaction and acceptability as compared to vaginal route.