Publication:

Hyperuricemia and maternal outcome in pregnancy induced hypertension: prospective study in a tertiary care center in Mumbai, India

Background Pregnancy induced hypertension, preeclampsia, eclampsia are serious complications of pregnancy. They are the leading causes of morbidity and mortality in the world and one of the leading causes for perinatal mortality also. It is the systemic disease affecting all vital organs including the fetus. Estimation of biochemical markers can give us the indication of the severity and prediction of the outcome. Serum uric acid is the end product of purine metabolism, amongst others like creatinine, LDH, transaminases.

Methods It was a type of prospective descriptive study. The present study was conducted in department of obstetrics and gynecology, Tertiary care hospital, Mumbai, Maharashtra, India.

Results Pregnancy induced hypertension was most common in age group of 20-25 years, most common complication was preterm delivery which accounts for 43% of maternal complications. 60% of the cases with IUFD had serum uric acid level 8-8.9 mg/dl, 3% of the patients had HELLP syndrome.

Conclusions We found severity of complication associated with raise in serum uric acid levels.