Publication:

Correlation between HbA1c level and LDL cholesterol level in ischemic stroke patients

Background Defects in insulin action and hyperglycemia could lead to Dyslipidemia in patients with diabetes.

Methods Cross sectional study carried out in patients presenting with ischemic stroke to medicine emergency unit of the LLRH Hospital from January 2018 to October 2019.Patient of age group 40-80 years The subjects in the present study were 450 patient comprised of 235 cases with ischemic stroke of age group of 40-80 years and 215 health y controls of age group of 40-80 years.

Results The correlation between these two variable as elicited from data obtained from study and, is significant (p<0.0001). The sensitivity of this correlation in the context of ischemic stroke is 75%, while the specificity is 60%. However, an impressive negative predictive value of 91% suggests a beneficial effect of normal or well controlled diabetes and Dyslipidemia. Conversely, a modest positive predictive value of 29% does not appear to help in utilizing this correlation as a measure of future likelihood of ischemic stroke. p value 0.00005 inference-highly significant.

Conclusions Study show statistically significant association (p < 0.001) of increased levels of HbA1c and LDL-C in patients of ischemic stroke.