Publication:

Histopathological correlation of abnormal uterine bleeding in perimenopausal women

Background Current study designed to identify the causes of abnormal uterine bleeding( AUB) in perimenopausal women and also to correlate with their histopathological examination.

Methods A prospective study of 65 perimenopausal women with complaint of AUB with age group ranging from 40 to 1 year within menopause those are attending to department of gynaecology of Narayana Medical College & Hospital, Nellore. Clinical examinations between the parameters were analysed. Histopathological examination report was also correlated with clinical examination and ultrasonography.

Results Out of 65 women, 11 (16.9%) were primiparas, 36 (55.38%) were para 2, 18 (27.69%) were para 3 and above. The frequent menstrual abnormality seen in perimenopausal women is heavy menstrual bleeding i.e., 41 (63%) women out of 65 women, 14 (21.53%) had polymenorrhoea, 9 (13.84%) had oligomenorrhea, 6 (9.23%) had postmenopausal bleeding, 4 (6.15%) had intermenstrual spotting. Most common type of endometrial pattern is proliferative endometrium. Out of 65 perimenopausal women, 23 (35.38%) had proliferative type of endometrium, 20 (30.76%) women had secretory pattern, 9 (13.84%) had typical simple endometrial hyperplasia, 4 (6.15%) had atypical simple endometrial hyperplasia, 3 (4.61%) had adenomyomatous polyp, and 6 (9.2%) women had irregular ripening.

Conclusions The present study shows that Histopathological examination is mandatory in all cases of AUB in perimenopausal age. 66.14% had benign pathology which can be managed by hormonal therapy or conservative surgical modalities which alleviates need for unnecessary hysterectomy.