Original Research ArticleInternational Journal of Reproduction, Contraception, Obstetrics and Gynecology

Publication:
Determinants of the survival of patients operated on for breast cancer at the Yaoundé Gyneco-Obstetric and Pediatric Hospital

Int J Reprod Contracept Obstet Gynecol. 2026;15(7):2410-2415.DOI10.18203/2320-1770.ijrcog20262084

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Abstract

Background In Cameroon, breast cancer remains a real public health problem and 5-year survival varies from 30 to 62%. Surgery improves survival. This study was conducted to determine that apart from surgery, what are the determinants of the survival of breast cancer patients at YGOPH.

Methods This was a descriptive study with historico-prospective collection of data from breast cancer patients at YGOPH (2010-2020). Kaplan-Meier estimated survival and Cox regression looked for factors associated with survival. The origin date was the date of the surgery and the end date was the date of death or the latest news.

Results The mean age of the 166 patients operated on was 48.27±12.44 years. About 48.2% had stage 4 (T4), 59% had lymph node invasion and 10.8% had metastases. Radical surgery was performed in 92.2% and 20% presented tumor recurrences. The 5-year survival was 62%. Independent factors associated with reduced survival were breast pruritus (HRa=9.74; p=0.004), retroareolar location of the tumour (HRa=2.5; p=0.035), lymph node invasion (HRa=2.66; p=0.008) and tumour recurrence (HRa=7.57; p=0.000).

Conclusions The 5-year survival was 62%. Factors associated with reduced survival were breast pruritus, retroareolar location of the tumor, lymph node involvement, and tumor recurrence.

Keywords

Affiliations

  1. Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon; Yaoundé Gyneco-Obstetric and Pediatric Hospital, Yaoundé, Cameroon
  2. Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Garoua, Camaroon; Garoua Regional Hospital Center, Garoua, Camaroon
  3. Department of Internal Medicine and specialities, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon; Yaoundé General Hospital, Oncology unit, Yaoundé, Cameroon
  4. Department of Internal Medicine and specialities, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon; Yaoundé Teaching Hospital, Anesthetists and reanimation unit, Yaoundé, Cameroon
  5. Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon
  6. Department of Internal Medicine and specialities, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon
  7. Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon; Yaoundé Central Hospital, Yaoundé, Cameroon
  8. Yaoundé Gyneco-Obstetric and Pediatric Hospital; Oncology Unit, Yaoundé, Cameroon
  9. Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon; Hospital Center for Research and Application in Endoscopic Surgery and Human Reproduction, Yaoundé, Cameroon

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