Publication:

Prescription pattern and rationality of drugs study of patients of OPD (outpatient) of orthopedics Department of RKDF Medical College Hospital and Research Centre, Bhopal, MP, India

Background To study the prescription pattern of drugs prescribed to patients of OPD of orthopedics department and to analyze the rationality of drugs prescribed by doctors of RKDF MCHRC, Bhopal, MP, India.

Methods A prospective, observational study was planned for 200 patients selected in the year 2015. Collected data were entered in a predesigned forms downloaded from WHO website. Rationality of drugs prescription was analyzed using WHO drug utilization and prescription indicators. For generic drugs reference NLEM 2011 and for cost analysis, Drug Today 2014 was used.

Results out of 200 patients, 41%were male and 59% were female. Average numbers of drugs prescribed per prescription was 3.3. Most commonly prescribed drug was Analgesics an Anti-inflammatory (37.1%) in oral as well as Intramuscular injections and Topical forms, Gastric acid inhibitors (15.4%), Muscle relaxants (12.1%) Calcium and Vitamin D, glucosamines (12.1%), Antimicrobials (8%), Steroids (1.8%), Enzyms serratiopeptidase (1.8%). Most commonly prescribed Analegsic was FDC of Trypsin+ Rutoside+ Bromelin+ Diclofenac (30.6%) followed by FDC Acceclofenac+ Paracetamol+ Seratiopeptidase (15.9%), followed by FDC Tramaodol+ Paracetamol (11%).Drugs prescribed in generic form were 0%.Average cost of treatment was INR 600 per prescription. Most common route of drug prescription was 1. Oral route 81.7%. 2. Topical 6.4%. 3. Injectable intramuscular 6.2% and intra articular 5.7%. Duration of treatment was prescribed in 81%. Frequency of drug administration was mentioned in 100% of prescriptions. EDL prescription was 81%. FDCs were 35%.

Conclusions There was Poly pharmacy. Drugs prescribed in generic form were very low. Drugs prescribed from NLEM were 81%. CMEs on Rational drug therapy to doctors working in orthopedics department should be conducted to promote rational use.