Publication:

A comparative study on the efficacy of saline infusion sonography and transvaginal sonography in abnormal uterine bleeding in premenopausal females

Background Saline infusion sonography (SIS) and transvaginal ultrasonography (TVS) were widely used techniques for evaluation of cases with abnormal uterine bleeding (AUB). However, the superiority of these two techniques in terms of accuracy remains a question.

Methods A total of 45 cases with AUB were subjected to both TVS and SIS and analysed for endometrial polyp or submucosal fibroids. The results of the imaging were compared with the histopathological results of the endometrium of the same patient. The data was analyzed using SPSS - Version 19.

Results In diagnosing thickened endometrium, diagnostic accuracy of TVS was reported as 91.1% with sensitivity (Sn), specificity (Sp), positive predictive value (PPV) and negative predictive value (NPV) of 96.7%, 78.6%, 90.9% and 91.7%, respectively. Similarly, for SIS, diagnostic accuracy (DA) was 93.3% with Sn, Sp, PPV and NPV were 96.7%, 85.7%, 93.8% and 92.3%, respectively. In adenomyosis, diagnostic accuracy of TVS was reported as 95.6% with Sn, Sp, PPV and NPV of 100%, 94.7%, 77.8% and 100%, respectively. Similarly, for SIS, Diagnostic accuracy was 100% with Sn, Sp, PPV and NPV were also 100%. In diagnosing fibroid, diagnostic accuracy of TVS was reported as 100% with Sn, Sp, PPV and NPV of 87.5%, 100%, 100% and 97.4%, respectively. Similarly, for SIS, diagnostic accuracy was 100% with Sn, Sp, PPV and NPV were 100%, each.

Conclusions We infer that SIS is found to be better efficacious in diagnosing different pathologies of AUB cases compared to TVS among the premenopausal women.